Ampligen and hypometabolism

paolo maccallini


A few days ago Naviaux and colleagues have provided convincing proofs for the presence of an hypometabolic state in chronic fatigue syndrome (CFS) patients, with a pattern opposite to the one seen in response to acute infections. Naviaux et al. express the hypothesis that the metabolic shut down described in their paper “may represent a fundamental response to oppose the spread of persistent viral and intracellular bacterial infections” (Naviaux RK et al., 2016).

CFS is a condition without a definitive cure, although some pharmacological interventions have shown some efficacy in subgroups of patients. One of them is rintatolimod (brand name: Ampligen), a viral double stranded RNA (dsRNA) which selectively binds to toll like receptor 3 (TLR3), thus contributing to the induction of antiviral defenses (Gowen, BB et al., 2007). Approximately 30-40% of CFS/ME patients can be expected to respond beneficially to rintatolimod, according to the…

View original post 202 altre parole



Effettua il login con uno di questi metodi per inviare il tuo commento:


Stai commentando usando il tuo account Chiudi sessione /  Modifica )

Google photo

Stai commentando usando il tuo account Google. Chiudi sessione /  Modifica )

Foto Twitter

Stai commentando usando il tuo account Twitter. Chiudi sessione /  Modifica )

Foto di Facebook

Stai commentando usando il tuo account Facebook. Chiudi sessione /  Modifica )

Connessione a %s...